Isochlorogenic acid A CAS NO.2450-53-5

Eucommia Ulmoides P.E. 98% Chlorogenic acid Product Name : Eucommia Leaf Extract Molecular formula: C16H18O9 CAS No: 327-97-9 Einecs No:206-325-6 …

Eucommia Ulmoides P.E. 98% Chlorogenic acid Product Name : Eucommia Leaf Extract Molecular formula: C16H18O9 CAS No: 327-97-9 Einecs No:206-325-6 Molecular weight: 354.31 Solubility: Good solubility in water Melting point:205-209 Appearance: Fine crystal powder Color: White Specific Rotation [α]: -36(c=1, H2O) Biological importance This acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100ug/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes. Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease . Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee, but is also found widespread in plants and can be isolated from the leaves and fruit . This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal. Biological importance This acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100ug/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes. Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease . Chlorogenic acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters.Chlorogenic acid, at concentrations as high as 100 um, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes. Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee; daily intake in coffee drinkers is 0.5-1 g. Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of cardiovascular disease. Chlorogenic acid has been proven in animal studies in vitro to inhibit the hydrolysis of the glucose-6-phosphate enzyme in an irreversible fashion. This mechanism allows chlorogenic acid to reduce hepatic glycogenolysis (transformation of glycogen into glucose) and to reduce the absorption of new glucose. In addition, in vivo studies on animal subjects have demonstrated that the administration of chlorogenic acid lessens the hyperglycemic peak resulting from the glycogenolysis brought about by the administering of glucagen, a hyperglycemiant hormone. The studies also confirmed a reduction in blood glucose levels and an increase in the intrahepatic concentrations of glucose-6-phosphate and of glycogen. Chlorogenic acid can be used as anti-infectious active ingredient, it has wide anti-virus, anti-bacteria effects, and has relatively lower toxicity and side-effects. It has obvious anti-infectious effects, and does not like to lead Anti-microbial Resistance. Due to its obvious anti-infectious effects, it not only can be used in pharmaceutical field but can be used widely in many other fields like food, feed additives, cosmetics also. More about our products, please visit us in our website: # If there are any further questions, please do not hesitate to contact me. We welcome your precious suggestions and any of your questions. Thanks for your interests in Nutramax Inc. Sincerely yours, Ms Gloria yin Sales Manager MSN: gloria@nutra-max.com Phone +86 731 2939659 Mobile +86 13755085426 Email: gloria@nutra-max.com Website: http://www. nutra-max.com Add: F25 jiahege builing, #217 wanjiali Road, changsha, Hunan, China 410016